Dulbecco's Modified Eagle's Medium (DMEM) is a modification of Basal Medium Eagle (BME), containing four-fold concentrations of the amino acids and vitamins found in BME, as well as additonal supplementary components. The original formulation of DMEM contained 1000 mg/L of glucose, but has since been raised in some modifications to 4500 mg/L, giving the terms "Low Glucose" and "High Glucose". Several other modifications over the years, in addition to the alternative glucose levels, have broadened the spectrum of cell types supported by DMEM.
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