Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.
Brefeldin A has been shown to increase CRISPR-mediated homology-directed repair (HDR) efficiency.
Store at -20℃
|Solubility||4 mg/mL (14.26 mM) in DMSO|
|Other Name||Decumbin, Ascotoxin, Cyanein, Nectrolide, Synergisidin, BFA|
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